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Genetic Machines

Posted on 04 March 2012 by Tea Server

And to Shakespeare I owe my vision of the world as a theater, wherein all humans are acting out their parts. - James Broughton

In the past couple of weeks, I have experienced and/or witnessed many occurrences that were very much out of the ordinary. Some delightful, and some horrific.

It all left me thinking that it would be very unfortunate if this were the only life we had and no one was looking out for us. Although, many believe that there is no one out there – and they have very solid accusations behind that declaration.

A close friend’s brother, who I knew since childhood, passed away today. He was epileptic.. And 22. Hearing of his unfortunate passing gave me a sense of loss, twisted my insides into a sickening knot and reminded me of all the hours we had spent together, all at once. I know that all God’s things must return to Him, but this was too soon. Maybe its all for the better. But if he was that young and could pass away at that age, just because he had some medical condition, there was seriously something wrong with nature and its life cycle.. And us humans as well for messing around with genetics and children just because we’re still ignorant, at large, of all the complexities that are involved. I know it’s basic concept boils down to ‘survival of the fittest’, it still makes me feel angry that why are not things like these watched out for?

I’m aware of the fact that genetic orders and messes, and environment issues are of our own doing, and that we all have freedom to do whatever the hell we want with our lives, but doing that upon the cost of your child, or even some random person on the street or even someone on the internet is intolerably unfair.

Genetics play such an important role in the character and, later, personality of each human being that one cant stress the phenomenon enough. Once a person has something written in the software code to his cells, its almost impossible to change course of those cells to behave in a desired fashion.

I do not believe we can blame genetics for adultery, homosexuality, dishonesty and other character flaws. - Jerry Falwell

This.. Is true as well. Genetics are merely particular personality traits borrowed from our ancestors for our coming generations, and so on. What a person decides to do in the short span of his life-time, he must face the consequences on his own and not blame some unknown force that may or may not have been there.

There isnt a minute on this planet that isnt overwhelmingly, and supremely, joyful somewhere and devastating elsewhere. We must always keep that in mind. Knowing that there will always be good and bad people, we must work in our lifetime to give the coming generation to bring out the best in them using our developed system and nature.

We must be humans, and not animals. 

Also, so proud of Sharmeen Obaid-Chinoy!!! The first ever Oscar that found it’s way home, because of her. I hope other men and women get motivated and start working on our, seriously lagging behind, cinematography sector.

Syndicated from: Her Sporadic Evolution

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Clicksor Review

Posted on 03 March 2012 by Tea Server

I just started using this great advertisement service, Clicksor. It lets you put ads on your blogs and websites, it doesn’t nearly pay as
good as other popular advertisement programs out in the market but it’s ads are more convincing and of good quality than many others, which means you get more clicks and you earn more.

Clicksor provides a wide variety of ad formats, ranging from bannersin-line text ads (ads targeted at keywords from your blog), pop-unders and interstitial ads (ads displayed before your website). Some of these ad formats like pop-unders and interstitial ads are very intrusive for the readers but they pay the most as well.

                                                                      click to enlarge

Clicksor also has a referral program which means you can earn 10% from a person you have referred to use Clicksor.

Overall, I think if you just got your AdSense account disapproved/disabled and you own a blog, then look no further sign up for Clicksor.

Syndicated from: Asad’s Blog

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Hold

Posted on 02 March 2012 by Tea Server

DSC05608

Last year. Monsoon. Home. Abbottabad.

Rains are beautiful. I have always had a awe-infusing contact and perception of it. I love how the dirt smells afterwards, and how everything looks perfect in its sparkly-clean splendour. Rain also enacts to characters: The Good, and The Evil.
The Good because it brings along several changes in the natural flow that are necessary for it to survive and prosper.
The Evil because when it does come onto you, it can damage many a things on the way. Like farms needs and fears it, animals are tormented, people shown some limits to their movement, and especially the people who are living in poverty see a lot of hardship due to rain.

But its oh-so beautiful, nonetheless.

Also, this picture is wonderful. I bolstered up the radiance slightly (since I dont have a camera that does that for me) to its more natural state when I took the picture. Love the fact that the camera thankfully directed its focus point to where I wanted it.

Syndicated from: Her Sporadic Evolution

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Nine Free resources for chest radiology

Posted on 29 February 2012 by Tea Server



Chest radiology is very important for diagnosis of many diseases in pulmonary medicine. In order to accurately identify the radiographic pattern of diseases, one needs to be able to understand the basics of chest radiology. Most of this valuable experience is gained at the hospital by interpreting the chest xray or CT scan films and then correlating the findings with the radiologist’s notes. However it is a tedious process and requires lots of commitment. I googled some of the online resources and was able to select some of the  resources for chest radiology that are available to all – for free.

1: Introduction to chest radiology.

This page is maintained by the Department of Radiology at  University of Virginia Health Sciences Centre. This page is directed at residents and medical students so that they can learn to interpret chest radiographs confidently. It has sufficient information for beginners to know about the technique of chest radiograph, identify the basic anatomy of thorax, interpret the chest radiograph successfully and locate the abnormality on an X-Ray film.

I like the systematic way in which the whole course is outlined for the readers. The images of chest radiographs are large, allowing visitors to understand what is being shown. This page should be bookmarked by residents and medical students before anything else.

 

2: Basic Chest X ray Review

This web page has been edited by W. Carpenter, Ph.D., M.D. of The Department of Radiology and Radiological Sciences, The Uniformed Services University of the Health Sciences Bethesda, MD USA. This website presents aa good technique of reviewing the Chest X ray film. The appropriate sections of a chest xray film are given along with the discussion making it easier for the readersto grasp the facts.

CT scan sesctions of different thoracic levels are also given at appropriate places.

 

3: G. Simon Collection of cases

This is a nice collection of  cases that is maintained by Ian Maddison. There is a variety to choose from. The x ray films have been properly grouped according to the patholgy. What I liked the most was the quality of the  x ray images. This way it made it easy to look at the images.

Nice effort.

 

4: Learning Radiology

This website is “conceived, designed, developed, is published, managed and maintained and its content is produced in its entirety by William Herring, MD, FACR”. I found this website to be a very detailed site dedicated to imaging of body systems. It contains huge information, Infact I could not browse it wholly because of time constraints. In addition to the x ray  images of chest diseases, this website also contains lectures in the form of slideshows and notes on different diseases. I liked the brief lectures and notes on chest diseases. Definitely a plus point. This site also contains flashcards for remembering differential diagnoses in chest diseases.

 

5: Radiology Tutorials

This website contains some very nice radiology tutorials on chest radiology. There is a link to a differential diagnosis “calculator” based on chest xray findings which I found interesting. The tutorials cover the lung anatomy and the malignancies of lung. I even found a link to radiology images for on-call doctors. 

Although it is a nice effort, but, the selection of font sizes and colors made it difficult for me to stay at the webpage.

 

6: University of Virginia Tutorials in Radiology

This is no doubt a blessing when it comes to medical imaging. This webpage has tutorials for interpreting a chest x ray film in ICU patients, cross-sectional images of thorax,  and High resolution CT scans of chest. I have found this one much more helpful in terms of establishing baseline knowledge when it comes to interpreting the chest radiographs or CT films.

 

7: Radiologic Pathologic Correlation in Chest Disease

It is a student project from the Faculty of Medicine at McGill University. The cases on this site are presented according to the pattern of the disease. For example all cases with pleural disease come together. Similarly all cases with consolidation are grouped separately. A specific radiographic pattern can be correlated with a CT scan image or other radiologic images.

Each case is divided into different sub sections like clinical history, radiographs, CT scan, Gross Morphology, Histology and then discussion. That way learning is enhanced. I highly recommend this page.

 

8: Chest X-ray Atlas

This is a nice collection of X-ray images by Arcot J. Chandrasekhar, MD, FRCP, FACP, FCCP of Loyola University Shicago. The atlas is organized into three sections. Pathology, Diseases and Radiological Signs.

This atlas was the first one that I ever found while searching for chest x-ray images on google and I really liked it. Dr Chandrasekhar also maintains another site which has tutorials on core topics in chest x-ray interpretation.

 

 9: Johns Hopkins – CTisUs

CT is us is created and maintained by The Advanced Medical Imaging Laboratory (AMIL) The AMIL is part of the Department of Radiology at the Johns Hopkins Medical Institutions in Baltimore, MD. This website contains thousands of CT images of body. The CT Chest images can be found here.

 

Although these resources can augment learning, I believe one actually learns at the workplace. These resources can not be substituted for the actual work experience at the hospital. T

hese are not the only ones on internet. There are large number of websites dedicated to chest radiology. What is your favorite one?

No related posts.

Syndicated from: Inspire.org.pk

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I Hate AdSense

Posted on 28 February 2012 by Tea Server

The last couple of days of mine were very terrible. Let me tell you all about it from the start. So, I started blogging, soon I found out that you can place ads here on your blog, so I said to myself
“Hey! this is kinda cool! I can write some blogs in my

leisure time and earn a few bucks at the same time. What can be awesom-er than that?”

So I applied for my AdSense account, at that moment I was like super excited and I was just thinking about how cool it would be to earn money this way. But then, I received an e-mail from Google that my account has been disapproved. I got really sad real quick. I applied for it again and again and every time I would apply it would give me the same reply “Your account has been disapproved”. Then I found out that my account had been disabled for “Invalid Activity”? I didn’t even had advertisements on my blog and my account got disabled for invalid activity? So just because of this bad experience with Google AdSense I now hate AdSense.

I’m not the only one who has suffered this type of problem, it turns out that many accounts from my country (Pakistan) have been disabled in the same way. I hope Google takes care of these problems but till then I need to find an alternative to Adsense.

Syndicated from: Asad’s Blog

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Perception Of Facts (For Now)

Posted on 21 February 2012 by Tea Server

Illustration by Jillian Tamaki

One of the many facets to human kind is that of perception and the reaction to your own and other people’s perception. That’s all well and good, but the problems resides in the fact that perceptions can be faulty. Now, to be completely immune to society’s damaging effects and even your own negativity is, quite frankly, impossible. Its better to realise and accept that fact and try to work on yourself to avoid situations that lead to misunderstandings.

Personally, I have come across hundreds of situations where the problem’s base were two things: perception and reaction.

When we see someone or some thing, we need to have an immediate image in our head of that thing/person for instant and later reference. Now human mind is such that we don’t just capture the appearance of the thing or person, we also register it’s character, movement, way of talking and general behavioural notes. Like I discussed earlier, people, like animals, need a description on others in order to protect themselves if needed. Even though there is nothing wrong with that, since perceiving is rather natural and you cant really help but let it take place. Albeit, it might be seen as unfair when someone perceives something even though there is not enough legitimate data to make it reality. But nonetheless, people do it anyway. Now, we cant really include people who intentionally perceive/portray things in such a way that it gives an unfair advantage to him/her and an unjust disadvantage to the person concerned as it would make the entire discussion, not impossible, but rather lengthy and complicated.

Now onto the reaction part. Let’s leave off general reaction to things for a while, as that might take ages and a separate blog to cover the whole topic, since its never simply a reaction, there’s all this psychological stuff going on inside our head.
So, then we are left with reactions to our own perceptions and other’s perceptions reeling back to us. Perception is such a thing that you just have no control over immediately, only after the whole act has been committed can we edit other’s and our own perceived imaginings (that is if we’re aware, but that’s besides the point). If, say, I was to perceive that some person wasn’t good at cooking. How would I react? Would I make fun of the person, let him be or completely ignore the idea? Or maybe teach him? If someone had the same idea about me and I knew about it, how would I react to that? Would I slam the said person in denial, try to become better at cooking, explain to him why or just take the hurt and ignore it altogether?

How we react to things contributes more to the person we’ll become than what we think, since actions have tentacles greater than thought, which is private and editable.  

Syndicated from: Her Sporadic Evolution

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بلاگ اسپاٹ میں فیس بک کمنٹ باکس شامل کرنا

Posted on 20 February 2012 by Tea Server

فیس بک کمنٹس آپ کے بلاگ پر تبصرہ کرنے کی بہترین سروس ہے۔جب کوئی کمنٹ کرتا ہے تو وہ اس کی فیس بک پروفائل پر بھی شائع ہوتی ہے لیکن یہ صارف کی مرضی کے مطابق ہوتا ہے۔اس تحریر میں بلاگ اسپاٹ کے لیئے فیس بک کمنٹس کو شامل کرنے کا طریقہ بیان کیا گیا ہے۔

سب سے پہلے ہمیں جو چیز اس کام کے لیئے درکار ہے وہ ہے فیس بک پر بنائی ہوئی ایپلیکیشن۔اگر آپ کو ایپلیکیشن بنانے کا طریقہ نہیں آتا تو آپ نیچے دیئے گئے طریقے سے دیکھ سکتے ہیں۔

ایپلیکیشن بنانے کے لیئے آپ اس لنک پر جائیں۔یہاں کلک کریں۔

اب آپ یہاں پر موجود بٹن Create New App پر کلک کریں۔کلک کرنے کے بعد کچھ اس طرح کی ونڈو آپ کے سامنے ظاہر ہوگی۔

اوپر دی گئی تصویر میں جس طرح لکھا گیا ہے بلکل اسی طرح آپ بھی اپنے بلاگ کا یا کوئی اور نام لکھیں۔اس کے بعد شرائط منظور کریں اور Continue پر کلک کریں۔

اب آپ کے سامنے سیکوریٹی کا ایک کوڈ آئے گا اسے لکھیں اور Submit پر کلک کریں۔

اب آپ سیٹنگ کی جانب چلے جائیں گے۔اب سیٹنگ میں یہ تبدیلیاں کریں۔

اس میں آپ اپنے بلاگ کے مطابق تبدیلیاں کریں اگر آپ اپنی ڈومین بلاگ اسپاٹ کی سروس کے ساتھ استعمال کر رہے ہیں تو آپ جہاں بلاگ اسپاٹ ڈاٹ کام لکھا ہوا ہے وہاں اپنی ڈومین لکھیں ورنہ یہی رہنے دیں۔نمبر دو میں آپ اپنا بلاگ کا ایڈریس لکھیں۔اور پھر Save Changes پر کلک کریں۔اور اب آپ اپنے ایپ کی آئی ڈی کو کاپی کر لیں۔

اب بلاگ اسپاٹ کی طرف جائیں۔سائن ان کریں اور ڈیش بورڈ سے Design ٹیب میں جائیں اور Edit HTML پر کلک کریں۔

اب آپ اپنے ٹیمپلیٹ کے اوپر موجود Expend Widget Templates پر کلک کریں اور اس کے بعد Ctrl + F کا بٹن اپنے کی بورڈ سے دبائیں اور نیچے دیئے گئے تین کوڈ میں سے کوئی کوڈ لکھیں۔

<data:post.body/>
<div class='post-footer-line post-footer-line-3'>
<p class='post-footer-line post-footer-line-3'>

اوپر دیئے گئے تینوں کوڈ میں سے آپ کو جو کوڈ بھی مل جائے اس کوڈ کے نیچے یہ کوڈ پیسٹ کردیں۔

<b:if cond='data:blog.pageType == "item"'>
<div id="fb-root"></div>
<script>(function(d){
 var js, id = 'facebook-jssdk'; if (d.getElementById(id)) {return;}
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}(document));</script>
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اب آپ اپنے ٹیمپلیٹ میں <head> تلاش کریں اور پھر یہ کوڈ پیسٹ کریں۔

<meta content='YOUR_FB_APP_ID' property='fb:app_id'/>

اوپر دیئے گئے کوڈ میں YOUR_FB_APP_ID کی جگہ اپنے ایپ کی آئی ڈی لکھیں۔

اب آپ اپنے ٹیمپلیٹ کوڈ میں <html تلاش کریں اور پھر ایک اسپیس دینے کےبعد یہ کوڈ پیسٹ کریں۔

xmlns:fb="https://www.facebook.com/2008/fbml"

اب آپ کے بلاگ اسپاٹ ٹیمپلیٹ میں فیس بک کمنٹ باکس شامل ہوگیا ہے۔

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Recent Advances in Pneumonia

Posted on 19 February 2012 by Tea Server



In the 19th century, pneumonia was regarded by William Osler as “the captain of the men of death”. Pneumonia affects approximately 450 million people worldwide and is responsible for 7% of world’s yearly deaths.

(Ruuskanen, O; Lahti, E, Jennings, LC, Murdoch, DR (2011 Apr 9). “Viral pneumonia”. Lancet 377 (9773): 1264–75.)

(Kabra SK; Lodha R, Pandey RM (2010). Kabra, Sushil K. ed. “Antibiotics for community-acquired pneumonia in children”. Cochrane Database Syst Rev 3 (3): CD004874. )

Pneumonia can be broadly classified into  Community Acquired Pneumonia or CAP, Healthcare Associated Pneumonia,  Hospital Acquired Pneumonia, ICU Acquired pneumonia, & Ventilator Acquired Pneumonia. Except for CAP all of the rest are called nosocomial pneumonias. Community Acquired pneumonia can be defined as

 an acute infection of the pulmonary parenchyma  that is associated with some symptoms of acute infection, accompanied by the presence of an acute infiltrate on a chest radiograph, or auscultatory findings consistent with pneumonia, in a patient not hospitalized or residing in a long term care facility for > 14 days before onset of symptoms.

Bartlett. Clin Infect Dis 2000;31:347-82.

Depending on the causative organism there are two types of presentation of pneumonia.

The “classical” presentation of pneumonia is characterised by sudden onset of CAP, High fever, shaking chills, Pleuritic chest pain, SOB, Productive cough, Rusty sputum which may be blood tinged and a poor general condition. The “atypical” presentation of CAP is characterized by gradual & insidious onset, low grade fever, dry cough, No blood tinged sputum and an over all good general condition. The usual causative organism that is responsible for classical presentation of CAP is S. Pneumonia. While many CAP caused by many different organisms like mycoplasma, legionella, chlamydiae etc has atypical picture.

Important risk factors for a complicated course or mortality in community acquired pneumonia include

  • Age > 65 years.
  • Co-morbid illnesses. like  CCF, CRF, Ischemic Heart Disease, Severe COPD,  & Concurrent Malignancy.
  • Post Splenectomy state
  • Altered mental State
  • Alcoholism
  • Immunosuppressive Therapy
  • Resp. Rate > 30 breaths per minutes
  • Blood pressure < 90/60 mmHg.
  • Hypothermia
  • Creatinine >150 mM/l or BUN >7 mm/l
  • Leucopenia <3,000/µl or leucocytosis >30,000/µl
  • Hemoglobin < 9 g/l
  • Albumin <30 g/l
  • Pseudomonas Aeruginosa or Staph. Aureus as the cause of pneumonia
  • Bacteremic Pneumonia
  • Multilobe involvement on CXR
  • Rapid radiographic progression of pneumonia defined as increase in the size of pulmonary opacity by 50 % or more within 36 hours.

Prompt idenitfication of the causative organism and immediate therapy can save life in many cases of CAP and the decision to hospitalize or to treat the patient at home is aided by many scoring systems that help determine the prognostic category of a patient suffering from CAP. PSI or PORT scoring and CURB-65 are the most commonly used scoring systems The risk of death within 30 days increases as the score increases in both these systems. I have found CURB-65 scores easier to calculate and determine than PORT score. But, as nothing is perfect in this world, researchers have found that the accuracy of CURB-65 and Pneumonia Severity Index for predicting outcomes is questionable.

(Intensive Care Med. 2007;33(12):2043-4.)

(Thorax. 2006;61(5):419-24.)

That lead to the search of new factors that could help identify the more sikc patients and therefore their timely management. Over the past few years, researchers have identified certain biomarkers that can help physicians as determinants of prognosis in community acquired pneumonia.

Some of these are:

  • CORTISOL
  • PRO-ADRENOMUDULLIN
  • D-DIMERS & COAGULATION PARAMETERS
  • PRO CALCITONIN
  • ENDOTHELIN-1

CORTISOL

The hypothalamic-pituitary-adrenal axis plays a major role in  regulating a patient´s response to infection. A strong association  between elevated cortisol levels, illness severity and the risk of death has been demonstrated. In previously healthy subjects, cortisol plasma levels have had a direct correlation with acute disease severity.

A study found a good correlation between the disease severity (as stratified by PSI scoring) and cortisol levels in patients presenting with Non-ICU CAP.  (Am J Respir Crit Care Med. 2007;176(9):913-20.)
Another study showed that in patients with severe CAP requiring ICU admission, baseline cortisol levels were better predictors of outcome than scoring systems like APACHE II, SOFA & CURB-65 and other routine lab tests. (Chest. 2008;134(5):947-54.)

Another study found that cortisol may be a useful biomarker for assessing the risk in patients with severe CAP in ER. Elevated cortisol levels (esp. more than 26 mcg/dl) are associated with disease severity and higher risk of death.  (J Crit Care. 2010;25(3):541.e1-8.)

PRO ADRENOMEDULLIN

Pro-adrenomedullin is a peptide produced by multiple types of tissue during physiologic stress. Its many functions include Vasoregulatory, Antimicrobial & Anti inflammatory activity. Increased levels of pro adrenomedullin have been found in body during infections. Increased production of ADM as well as decreased clearance by kidneys have been postulated as the mechanisms responsible for Increased pro-ADM. A recent study showed that pro-ADM levels increased with the increasing severity of CAP, classified according to PSI scoring. (Crit Care. 2006;10(3):96). Subsequently another multicenter prospective cohort study confirmed the prognostic value of  pro-ADM.( Chest.  2009;136(3):823-31.)

Recently a practical algorithm combining the CURB-65 scoring with pro-ADM levels in patients with CAP and non-CAP-LRTI has been proposed. (BMC Infect Dis. 2011;11:112). It (CURB-65-A) has been effective in accurately predicting adverse events and mortality in patients with CAP and non-CAP-LRTI. Patients in the lowest CURB-65 groups and with pro-ADM levels less than 0.75 nmol/l were at a very low risk of adverse events and mortality. Patients in the highest CURB-65 groups and pro-ADM groups (CURB-65-A risk Class III) had the highest risk of adverse events and mortality. Finally, patients with CURB-65 class 2 and pro ADM levels less than 1.5 nmol/l or CURB Classes 0-1 and pro-ADM levels between 0.75-1.5 nmol/l had intermediate risks. It looks promising, yet more studies are required before it can be added to CURB-65 algrithm.

 D-DIMERS

D-Dimers are the most studied coagulation parameters that have been evaulated in severe CAP. Elevated D-dimer levels can be seen in

  • DIC
  • Severe Sepsis
  • Thromboembolic events
  • Pregnancy
  • Liver diseases
  • Surgery & Trauma

In patients without clinical or overt evidence of coagulopathy, high d-dimer levels may indicate microvascular thrombosis and therefore disease severity. (Thromb Haemost.1987;57(1): 59-61.)
In a prospective observational study that evaluated 68 CAP patients that presented to the A&E, D-dimer levels were positively correlated with APACHE II, Pneumonia PORT scores and the length of hospital stay.  Mean d-dimer levels of hospitalized patients were higher than the non-hospitalized patients. It demonstrated that d-dimer is associated with disease severity and clinically relevant outcome.
(Blood Coagul Fibrinolysis. 2003;14(8):745-8.)

Another prospective observational study showed a direct relationship between d-dimer levels and outcome in CAP patients.
The mean d-dimer level in nonsurvivors was 3.786 ng/ml while in survivors the mean level was 1.609 ng/ml. There was a significant association between the presence of elevated d-dimer levels and PSI and APACHE II scores.( Am J Respir Crit Care Med. 2011;184(2):186-90.)  Addition of d-dimers increased the predictive ability of scoring systems like SOFA & APACHE II.
(J Crit Care. 2011;26(5):496-501.)

PRO CALCITONIN

New promising information suggests that pro-calcitonin (PCT), a precursor of calcitonin is released into the blood of persons with bacterial infections. This biomarker, released in blood, has been used to evaluate the severity & prognosis of CAP in patients and to de-escalate the antibiotic therapy. At levels of less than or equal to 0.25 µg/l, antibiotic therapy has been successfully discontinued in patients with pneumonia.

ENDOTHELIN 1

Endo thelin-1 is a potent vasoconstrictor agent primarily synthesized by endothelial cells. Endothelin-1 itself is unstable and rapidly cleared from circulation, however its precursor peptides can be detected in circulation. Recently a study assessed the diagnostic & prognostic value of pro-Endothelin-1 in patients with septic CAP.

In these patients, circulating ET-1 precursor peptide levels had a good correlation with the severity of CAP, as assessed by PSI and CURB-65 scores. (BMC Infect Dis. 2008;8:22). The pro-ET-1 levels can improve the prognostic accuracy CURB-65 scores in predicting adverse outcomes. Over all the discriminatory ability of pro-ET1 to predict death and ICU admission was significantly better that CRP & TLC.

 

I have briefly prsented the research that is done in this regard. The future looks promising however I am not much sure that thesenew factors will be able to help physicians all across the globe. It is because measurement of many of these factors is not universally available. and even if future research proves one or more of the above mentioned factors as helpful in predicting the prognosis of CAP in patients, the application of such criteria will be dependent on the availability of laboratory facilities for measurement of these substances and the patient affordability. At present, except for D-dimers, none of the above can be measured easily across the world in an OPD setting.

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Syndicated from: Inspire!!

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Hello Again!

Posted on 02 February 2012 by Tea Server

This wasn’t planned, it just so happened that I opened up my email tonight (which I don’t in normal circumstances), I was expecting an email from my aunt, but instead I found an email from ‘Amna Khan’, (my aunt’s name is also Amna so I was confused there for a little while). Anyway, I don’t [...]

Syndicated from: Living In Pakistan

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Tick-ling

Posted on 29 January 2012 by Tea Server

No one knows what makes your mind tick.. When you hear someone say something; read something in the morning newspaper; the bitterness of your morning coffee gets you thinking about bitter other-some-things.  


We all know that any sort of ‘ticking’ must have some emotion in the back of it all, which makes the ‘ticking’ longer and inspires an action, or feeling, from us.. That we may, or may not be proud of (but that’s another thing).
I have no idea what the scientific research on this says, but for me, its probably powered by emotions. For example, if I see someone fighting for a good cause, I’d feel happy, proud and get inspired to do something like that or at least take some action in support to that. 

Getting ‘ticked’ (in a positive way) is always healthy, and oh-so-important for a human to grow. If a human being isn’t inspired by a certain-something, how will we ever do things and become the people we’re supposed to become? Even if, say, one’s forced to study or not to lie, would that change the person inside? Maybe, a little. But even that’d be a short term change, and very superficial. In order for a human to grow truly, and from within, one needs to be inspired by something.. And that’ll only happen when something/someone ticks the inspiration button on. 

Syndicated from: Her Spuh-rad-ic Evolution

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The Diarist In Me

Posted on 26 January 2012 by Tea Server

There’s something about public interaction/confrontation/appearance that creeps the shyer one’s out of social hangings. Maybe it’s just, maybe it isn’t. 


In the past few days I have been giving a go at writing. Even though I have been writing for a long while, although not on a regular basis, I never was confident in my writing, or my mental capability to do so. Recently though, I decided that it was important that I gave it a go and not worry about the outcome initially.. Because how will you know if you’re good, or bad, at something when you don’t take it seriously and test yourself out?


I always knew, deep in my gut, that I was never meant to be a diarist. You see, you need some kind of constant factor within yourself to be entertaining while at it. Even though I believe that everyone’s life is unique and worth even writing about.. Mine may not be all that charming written in cold, hard text – even if I’m the only one who thinks that, you always need it inside you to do something in order to be successful at it. 


To be a diarist, I think, you need to be a solid person from within, who’s a firm believer in what he believes in, and knows exactly how he feels about things (like my younger sister). I, on the other hand, am not at all that. I’d rather change all the time with no past records to prove that I have.. Experiment, even if it may be risky at times. There’s always a better opportunity in bold letters waiting for your attention, approval and action upon it. ‘Tis only the human brain that skips that, and goes instead to write his ego across the country in bold letters to have some sort of significance, deeper, and in many ways, better than others. 


I really don’t know why I cannot write posts that are much more entertaining, although they can be superficial and need little/no brains to muscle out concepts and ideas and perceptions through its lovely being. I wouldn’t say I was being arrogant.. Just that this is the sad truth that I have to live with and also, by. I’d rather that some lazy day I sit under the three with a diary in hand and writing all that has happened throughout the day.. But that doesn’t happen does it? Firstly because I don’t have many problems (thank God for that), secondly, I love life and refuse to be depressed/upset during it.. Even for a couple of hours.. Just doesn’t happen. So, instead I start writing about the reason behind any good/bad thing that has happened through the day and forget about the hurt and upsetting situation in a jiffy. Leaving me with no violent emotion.. And without that, how can I ever become a good diarist? 

Syndicated from: Her Spuh-rad-ic Evolution

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Yes! We Khan – Social Media Case Study Of Imran Khan Rally On December 25th, 2011

Posted on 24 January 2012 by Tea Server

The highly successful Jalsa of 25th December, 2011 organized by Pakistan Tehreek Insaf was a major social media milestone for Pakistan. By using a disruptive technology in early markets, PTI has upset the status quo, catapulting a man who did … Continue reading

Syndicated from: iStratagem

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Its Really The Tiny Things

Posted on 24 January 2012 by Tea Server

A meow awakens me each morning followed by, the cutest thing cats do, the pressing of one paw at a time on my back. Forcing my head from under the quilt, just to give Cherie the okay signal with a look, I see the most prettiest face on earth (at least to me) and I am taken over with emotion, and of course everyone knows what happens after that.

After that, breakfast comes along with the blessings of a heater (which people in villages cannot enjoy; I would know). I cant describe how wonderful it feels when an external things warms one up, I don’t take it as a do-it-yourself sort of thing, should be understood that external things are supposed to warm a human up.

Anyway, all these small things and, of course, the realisation of their existence, make my day so much more worth being in and a part of. Which leads me to thinking of people taking their days for granted (wont even mention the people who don’t have anything to take granted for, that’s a whole new chapter). How sad are they? I mean, you need to be completely dead from within to be not effected by all the small things that enrich our days and make them different from the previous, even if it is slightly. I may have been exaggerating slightly in the previous sentence, but it has to be somewhat true. You need to be completely self centred to not be able to see that. Of course, there’s a very big collection of people who have never been encouraged, supported or simply motivated enough to be involved in something bigger than their own tiny issues that held no significance to the amount of stuff taking place around them.


Moral of the story: Boo to taking-for-grant-ers. 

This may be considered as hate mail, if you’re very sensitive. But if you’re not, then CHANGE. No one gets lucky with a dead person. 


Syndicated from: Her Spuh-rad-ic Evolution

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بلاگ اسپاٹ میں REPLY بٹن شامل کرنا

Posted on 23 January 2012 by Tea Server

یہ تحریر میں اس لیے لکھ رہا ہوں کہ یہ سوال میرے سے علی حسن صاحب نے کیا تھا کہ ”کیا کوئی ایسا پلگ ان بھی ہے جو بلاگر میں تبصرے کا جواب دینے کی آپشن دے، یعنی بجائے کہ تبصرے کا جواب دینے کے لیے نیا تبصرہ کیا جائے اسی تبصرے میں ہی جواب دے دیا جائے؟؟“۔تو اس سوال کا جواب دینے کے لیے میں نے سوچا کہ ایک تحریر ہی لکھ دی جائے کیوں کہ اس سے کسی اور کا بھی فائدہ ہوسکتا ہے۔

اس بٹن یعنی REPLAY بٹن کو ظاہر کرنے کے لیئے آپ کو اپنے بلاگ اسپاٹ بلاگ کی آئی ڈی معلوم ہونا ضروری ہے۔اگر آپ کو آئی ڈی نہیں معلوم تو اس کا سب سے آسان طریقہ یہ ہے کہ آپ DESIGN والے ٹیب میں جائیں اور یاد رکھیں کہ آپ صفحہ PAGE ELEMENTS میں ہی ہیں۔آپ اس پیج کا ایڈ ریس دیکھیں اپنے ایڈریس بار میں آپ کو یہاں پر بلاگ کی آئی ڈی نظر آئے گی،اس آئی ڈی کو یہاں سے کاپی کر لیں اور نیچے فراہم کیئے گئے کوڈ میں پیسٹ کردیں۔

سب سے پہلے تو آپ بلاگر میں سائن ان ہوں،اس کے بعد آپ ڈیش بورڈ میں کچھ اس طریقہ سے جائیں >> DESIGN >> EDIT HTML اس کے بعد آپ اس صفحہ پر موجود چیک باکس EXPEND WIDGET TEMPLATES کو چیک کردیں یعنی مارک کردیں۔

اب آپ اپنے براؤزر میں کی بورڈ کے ذریعے بٹن CTRL + F دبائیں اور اس میں یہ کوڈ داخل کریں۔

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تلاش کرنے کے بعد آپ کو جو لائن نظر آئے گی اس لائن کے نیچے یہ کورڈ پیسٹ کردیں۔

کوڈ کاپی کرنے کے لیے یہاں کلک کریں۔

اس کوڈ میں جو الفاظ واضح کر کے لکھے گئے ہیں انہیں اپنی معلومات سے مکمل کریں۔اور اب آپ دیکھ سکتے ہیں کہ کمنٹ ( تبصرہ ) کے نیچے REPLY کا بٹن نظر آنے لگے گا۔امید ہے آپ اس تحریر سے اپنا مقصد حاصل کر چکے ہوں گے۔

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